Century: Golem Edition is a re-themed version of Century: Spice Road set in the world of Caravania. In Century: Golem Edition, players are caravan leaders who travel the famed golem road to deliver crystals to the far reaches of the world. Each turn, players perform one of four actions:

- Establish a trade route (by taking a market card)
- Make a trade or harvest crystals (by playing a card from hand)
- Fulfill a demand (by meeting a victory point card's requirements and claiming it)
- Rest (by taking back into your hand all of the cards you've played)

The last round is triggered once a player has claimed their fifth victory point card, then whoever has the most victory points wins.